Puracyp: Your outsourcing solution for fast, economical, and uncomplicated answers to drug metabolism issues
We are a biotechnology company dedicated to the development of methods that permit rapid and efficient assessment of the safety of new drugs prior to their clinical usage. Specifically, we offer cell-based systems to examine nuclear receptor activation, the first step in drug-metabolizing enzyme induction. Our other services include studies to determine the metabolic stabilily, kinetics of metabolism, P450 reaction phenotyping, inhibition of P450 oxidation, and P-glycoprotein binding of new chemical entities. We have devised systems that are high in throughput without sacrificing quality. Puracyp also offers tools to study oxidative drug metabolism in vitro, including human liver microsomes that have been extensively characterized for P450 enzyme expression and specific antibodies to the individual P450s.
Press Releases
European, Australian and New Zealand patent for PXR was awarded to the Salk Institute. Puracyp signed a license agreement with The Salk Institute in 2004 for the exclusive use of SXR/PXR to screen xenobiotics for receptor activation which now includes coverage in Europe and the South Pacific as well as the United States
Puracyp adds Dr. Jerome M. Lasker as Director of Laboratory Operations to expand ADME services and product offerings. Dr. Lasker has recently joined our team to facilitate the expansion of the ADME services and drug metabolism-related products we now offer to streamline your own research.
Puracyp signed a license agreement with XenoPharm, Inc. in January 1, 2009 for the use of XREM. This CYP3A4 promoter is part of Puracyp's cell lines used to screen xenobiotics for PXR activation
Events
Puracyp now offers new products and expanded ADME services. Our ADME services now include studies on various facets of oxidative drug metabolism. Our new products include antibodies to the drug-metabolizing P450 enzymes and human liver microsomes with defined P450 enzyme content.